Santa Cruz de la Sierra, Bolivia - Travel Guide

By MupDay - the planner that does the research for you.Directions from stop to stop included - all free.

Plan a free trip to Santa Cruz de la Sierra

Updated: 2026-10-11

Santa Cruz is Bolivia's largest and most vibrant city, offering a fascinating blend of modernity and traditional culture. Come enjoy the tropical climate, colorful markets, and impressive colonial architecture.

Top things to do in Santa Cruz de la Sierra

Things to do in Santa Cruz de la Sierra include Plaza 24 de Septiembre, Metropolitan Cathedral Basilica of San Lorenzo, Biocentro Güembé. Here are 15 places worth knowing, with a short note on each.

Want all of these sorted into days?

MupDay splits them by proximity and real opening hours, with no zig-zag - directions from stop to stop included. All free.

Build an itinerary for Santa Cruz de la Sierra

Frequently asked questions

What are the top things to do in Santa Cruz de la Sierra?

Plaza 24 de Septiembre, Metropolitan Cathedral Basilica of San Lorenzo, Biocentro Güembé, Monumento Cristo Redentor, Museo Guaraní, Museo de Arte Contemporáneo and 9 more. Plaza 24 de Septiembre: The city's bustling main square, surrounded by historic buildings and perfect for people-watching.

Which museums are worth visiting in Santa Cruz de la Sierra?

Museums worth visiting in Santa Cruz de la Sierra: Museo Guaraní, Museo de Arte Contemporáneo and Museo de Historia Natural Noel Kempff Mercado.

Destinations near Santa Cruz de la Sierra

All guides in Bolivia →

All city guides →

Ready to plan Santa Cruz de la Sierra?

Build an itinerary for Santa Cruz de la Sierra